BIOANALYTICAL ASSAY DEVELOPMENT
 Marin Biologic provides a wide variety of bioanalytical assay development for small and large molecules that includes potency for drug release, in vitro toxicology, methods requiring antibody recognition, pharmacokinetics (PK) drug binding studies, and patient immune responses to drugs.
Assay development requires sensitive, accurate and reproducible assays.
- New fully-equipped laboratory facility to handle your most urgent project
- Quick turnaround time for your bioanalytical assay development
- Expertise in multiple areas, such as biochemistry (for large molecule drugs or excipients) and cell biology (for potency assays)
- Experienced scientists
- Proven success to help you meet your goals.
Often our client's drugs are manufactured and are tested in excipients. Some assays require that the drug be detected in biological matrices such as serum, plasma, whole blood, urine or various tissues. Our many years of assay development have led to a level of expertise in these complex matrices that enable the success of your assay development.
Marin Biologic has developed assays from rodents, canines, primates and human matrices. After discussing the requirements of the assay with you (e.g. sensitivity, drug solubility) our scientists can suggest methods that are best suited for a customized assay.
Our scientists have also improved on previously developed assays, such as sensitivity, selectivity, enhance signal to noise, and extractions. Depending upon your requirements, different levels of bioanalytical assay development will be performed:
- Iinitial assay
- More optimized assay
- GLP/GMP validated assay, suitable for submission to the FDA for an IND or NDA filing.
- MSD, Meso Scale Discovery platform for increased sensitivity, expanded range and decreased matrix effects.
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