|
Stem cell therapy development is an exciting
area of research that promises the future treatment of many
diseases. Since this area in drug development is in its infancy,
there are many hurdles to overcome. The scientists at Marin
Biologic are here to assist you in the many phases of your
stem cell therapy development. We can culture adult or embryonic
stem cells and monitor the differentiation markers for your
therapy development. Please think of Marin Biologic as your
stem cell research laboratory.
Many scientific considerations are involved
with stem cell replacement therapy. We can aid you in the
following scientific endeavors; microenvironment, transfecting
markers into adult or embryonic stem cells, replacement of
specific molecules, etc.
Microenvironment may contribute to stem
cell "homing" events or differentiation. Our scientists
can study microenvironments, whether generated in culture
or from exogeneous tissue, and their effects on stem cell
differentiation using in vitro methods. Transfecting
adult or embryonic stem cells with a genetic marker to follow
their "homing activities" can be performed prior
to inoculation in vivo. Development of "homing"
stem cells as a delivery vehicle for cancer therapy can be
undertaken at Marin Biologic. Replacement therapy for hormone,
cytokines and metabolic intermediates can be implemented using
stem cell therapy. Insulin production is a key target for
diabetes therapy using stem cells because of their "normal"
detection of glucose levels and "normal" synthesis
and release of insulin. Our scientists can help you to develop
stems cells that synthesize your therapeutic molecule by initiating
differentiation and monitoring specific production.
To implement stem cell therapy, there must
be many levels of investigation ranging from the cell
culture of stem cells, triggering differentiation, expanding
stem cell cultures to large scale cultures for replacement
therapy, determining whether immunocompatibility of embryonic
stem cells is retained for transplant, down regulating HLA
molecules in adult stem cells, etc. The scientists at Marin
Biologic are very experienced and creative in cell
biology and can bridge this field with molecular
biology and biochemistry
for potential cell therapy and assay development.
|
Stem Cell Therapy Development 