Cutting Edge MarinBio Science Newsletter
July 23, 2026
Looking for a partner with 30 years of proven expertise in taking drugs from development to validation and
FDA approval?
Contact us @ 415.883.8000
Lung cancer is among the most lethal malignancies worldwide, with limited therapeutic success despite advancements in immunotherapy. Immune checkpoint inhibitors (ICIs), particularly those targeting PD-1/PD-L1
A groundbreaking study published in the journal Cell has unveiled a pivotal role for the immune system in suppressing the spread of breast cancer
A groundbreaking study published in Molecular Therapy by a research team led by Dr. Fatima Bosch at the Universitat Autònoma de Barcelona has introduced an
Researchers from the German Cancer Research Center (DKFZ), CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, and Heidelberg University Medical Faculty
Cancer immunotherapy, particularly immune checkpoint blockade (ICB), has transformed the treatment of advanced cancers, notably melanoma. However, many melanoma patients show limited responses or suffer
Researchers from the University of Oklahoma Health Sciences Center and Memorial Sloan Kettering Cancer Center have recently published a comprehensive study in the journal Cell
A complete cure for HIV/AIDS remains elusive, but recent amazing progress in therapy is bringing new hope. This article describes recent breakthroughs in HIV therapy,
Researchers from AstraZeneca have unveiled new insights into the behavior of trivalent proteolysis-targeting chimeras (PROTACs), challenging previous assumptions about their efficacy in targeted protein degradation.
From PROTACs to PROTAVs: A New Era in Cancer Vaccine Development Cancer immunotherapy, particularly immune checkpoint blockade (ICB), has transformed the treatment of advanced cancers,
You might feel perfectly healthy, but did you know that your organs age at different rates? It’s possible for one organ to be significantly older
Autoimmune diseases occur when the immune system mistakenly targets and attacks the body’s own cells and tissues. Advances in immunotherapy have led to innovative treatments
Targeted protein degradation, particularly through proteolysis-targeting chimeras (PROTACs) has emerged as a revolutionary approach in drug discovery and development over the past two decades. This
This list provides a summary of recent patent publications from April 2023 to February 15, 2024, focusing on scientific information. Please note that it may
Introduction Beta-Propeller Protein-Associated Neurodegeneration (BPAN) is a devastating and ultra-rare neurodegenerative disease linked to mutations in the WDR45 gene. Manifesting primarily in females, BPAN results
Introduction Oncolytic viruses (OVs) represent a class of viruses that specifically target and destroy cancer cells while leaving normal healthy cells unharmed. These viruses can
Introduction Gene therapy has made significant strides in recent years with various viral vectors being developed to deliver therapeutic genes to target cells. While adeno-associated
Introduction PROTAC (PROteolysis TArgeting Chimera) is a novel therapeutic approach that leverages the cell’s natural protein degradation machinery to selectively target and degrade disease-causing proteins.
Introduction An Antibody-Drug Conjugate (ADC) is a precision cancer therapy that harnesses the specificity of a monoclonal antibody to target cancer cells linking it to
Flow Cytometry in Cell-Based Assays and Drug Discovery: A Focus on Cytokine Analysis Flow cytometry is a powerful analytical technique that combines principles of fluid
Blog Highlights: What causes autoimmunity? Antibodies and BiSpecific antibodies for autoimmunity Cellular treatments for autoimmunity How can Marin Biologic Laboratories help you What Are Common
As new cases of COVID-19 soar, experts warn about the newly emerged COVID subvariant BA.5, a sub-lineage of BA.2. Subvariants of Omicron BA.1 emerged in
DO YOU NEED A GMP VALIDATED POTENCY ASSAY? Does the FDA or your Quality Department tell you that to release your manufactured lots you need
Radiopharmaceutical Drugs Radiopharmaceutical therapy (RPT), also known as radioligand therapy (RLT), is emerging as a novel and promising approach to combat cancer. This innovative therapeutic method harnesses the potency of
Blog Highlights: Why do we age? How to delay or prevent aging Cell-Based Assays for Aging How can Marin Biologic Laboratories help you with bioassays?
Antibody Drug Conjugate (ADC) Drugs Kill Target Cells What is an Antibody Drug Conjugate (ADC)? What potency assays are needed for an ADC? How can
CANCER HIGHLIGHT | Potency Assay for Bispecific Antibody Constructs Blog Highlights: What is a bispecific antibody? How is a potency assay for a bispecific antibody for cancer
Introducing Our Cutting-Edge ELISA Method Bispecific antibodies are a groundbreaking class of molecules that have revolutionized targeted therapies. These unique antibodies are designed to simultaneously
What are PROTAC degraders or protein degrader drugs? Proteolysis Targeting Chimeric (PROTAC) drugs are a type of novel heterobifunctional molecules that utilize the ubiquitin-proteasome system
Gene therapy has emerged as a promising approach to treating rare genetic disorders and unmet medical needs. Adeno-associated virus (AAV)-based gene therapy is the leading
Invention: The researchers from Adverum Biotechnologies. (Redwood City, CA) have developed a method for generating eukaryotic cell libraries for screening mutant AAV capsid proteins. Background