Download the full article (PDF) Introduction CAR-macrophage therapy is an emerging cancer treatment strategy that engineers macrophages to express chimeric antigen receptors (CARs), redirecting their natural tumor-homing, phagocytic, and immune-activating functions against cancer. Unlike CAR-T cells, which primarily kill through cytotoxicity, CAR-macrophages are designed to infiltrate solid tumors, engulf cancer cells, and remodel […]
Download the full article (PDF) Introduction CAR-macrophage therapy is an emerging cancer treatment strategy that engineers macrophages to express chimeric antigen receptors (CARs), redirecting their natural tumor-homing, phagocytic,
Download the full article (PDF) Introduction Cancer is fundamentally a disease of cellular heterogeneity. Tumors are composed of genetically and phenotypically diverse malignant cells, surrounded by stromal and immune
Download the full article (PDF) Introduction Subunit vaccines are increasingly at the forefront of cancer immunotherapy. They are termed ‘subunit’ vaccines because they are constructed to combine only the
Download the full article (PDF) MarinBio Blog Advances in Gene Therapy for Ultra-Rare Genetic Disorders Introduction Ultra-rare hereditary genetic disorders represent some of the most challenging conditions in medicine. Affecting
Download the full article (PDF) MarinBio BLOG The CAR-Treg Rebellion Chimeric Antigen Receptor (CAR)-engineered regulatory T cells (CAR-Tregs) represent a distinct and rapidly emerging frontier in cellular immunotherapy, offering
Download the full article (PDF) INTRODUCTION Cancer remains a leading cause of morbidity and mortality worldwide, and the need for therapies capable of addressing complex molecular networks is more
Introduction Cancer treatment has undergone a dramatic transformation in recent years, moving from broad cytotoxic chemotherapies toward molecularly precise strategies tailored to specific genetic, epigenetic, and proteomic vulnerabilities. The
G Protein Coupled Receptors (GPCRs) represent a vast and diverse family of membrane proteins that are central to the regulation of human immune cell function. These receptors mediate responses
Introduction Autoimmune diseases constitute a complex group of disorders in which immune system dysregulation leads to chronic inflammation and tissue damage. Among these diseases, rheumatoid arthritis (RA), inflammatory bowel disease
Flow cytometry stands at the forefront of cancer diagnostics and therapeutics, transforming oncology practice through its capacity to dissect cellular and molecular complexity. By enabling the simultaneous measurement of
