Small Molecule Drug Uptake Assays

  • Radioactive Tracer Assays

Uses radiolabeled drugs to track uptake into cells. Common isotopes include 14C, 3H, 125I, and 32P.

  • Fluorescent Assays

Employs fluorescently labeled drugs. The uptake is measured using quantitative fluorescence microscopy or plate readers.

Analyzes the uptake of fluorescently labeled drugs by measuring fluorescence intensity in individual cells.

Uses antibodies specific to the drug to quantify its uptake in cells.

Nanoparticle/lipid nanoparticle (LNP) uptake assays

Quantifies the uptake of fluorescently labeled or gold nanoparticles by cells.

Uses antibodies to detect and quantify specific proteins or markers associated with nanoparticle uptake.

DNA/RNA/Plasmid uptake assays

Measures the expression of reporter genes encoded by the DNA/mRNA/plasmid.

Quantifies transgene expression by its mRNA.

Measures fluorescence intensity of cells transformed with plasmids encoding fluorescent proteins, quantifying uptake at the single-cell level.

Need Help or Have Questions on Cell-Based Assays?

Contact us to discuss the specifics of your project. Our team of experienced scientists is ready to assist you with tailored solutions to meet your unique needs. Whether you need help with assay development, FDA IND, stability study,  lot release approval, or other scientific endeavors, we are here to support you.
Contact us to learn more about our cell based assay services

We will initiate your project as soon as the proposal is approved and signed by you. Our streamlined process ensures a quick start, minimizing delays and maximizing efficiency. Fill out the form below to email us or click our live chat option to speak with a MarinBio Scientist and get your project underway.

Yes, we have over 30 years of expertise in developing and validating cell based assays for FDA IND, lot release or stability study approval. Our team can also liaise directly with the FDA on your behalf, ensuring a smooth and compliant process. Please contact us to learn more about how we can assist you with your assay development and FDA approval needs.

MarinBio scientists are experienced and creative in designing, developing, validating assays. Some of the assays we perform are listed below, but there are many more that we created, developed and validated. Give us call so that we may help you.

Need help or have questions on cell based assays?

Give us a call at 415-883-8000

Contact Us about Our Cell Based Assays Services

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