Cell Health Based Assays Offered by MarinBio​

Measures ATP

  • CellTiter Glo (CTG)

Measures Intracellular Reducing Potential

  • MTT Assay (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide)
  • XTT Assay (2,3-Bis(2-Methoxy-4-Nitro-5-Sulfophenyl)-2H-Tetrazolium-5-Carboxanilide)
  • MTS Assay (3-(4,5-Dimethylthiazol-2-yl)-5-(3-Carboxymethoxyphenyl)-2-(4-Sulfophenyl)-2H- Tetrazolium)
  • WST Assay (Water-Soluble Tetrazolium Salts)
  • Alamar Blue Assay (Resazurin Reduction Assay)
  • Lactate Dehydrogenase (LDH) Release Assay

Measures Live/Dead Cells

  • Trypan Blue Exclusion Assay
  • Propidium Iodide (PI) Staining for Dead Cells
  • AOPI (Acridine Orange for total cells, PI for dead cells)
  • Flow cytometry with vital stains
  • Crystal Violet Staining Assay, measures proteins and DNA
  • Neutral Red Uptake Assay, measures dye uptake into lysosomes of live cells

LIVE/DEAD Assay

  • Calcein-AM/Ethidium Homodimer-1 Assay
  • 51Cr Release assay

PROLIFERATION

Measures DNA synthesis

  • BrdU Assay (Bromodeoxyuridine Incorporation Assay)
  • EdU Assay (5-Ethynyl-2′-deoxyuridine Incorporation Assay)
  • 3H-Thymidine uptake

Measures cell growth

  • Above Cell Health Assays
  • Colony Formation Assay
  • Sulforhodamine B (SRB) Assay
  • Cell Counting Kit-8 (CCK-8) Assay

Measures cell division

  • CFSE Assay (Carboxyfluorescein Diacetate Succinimidyl Ester)

Necrosis/Apoptosis Assays

Necrosis Assays

  • Propidium Iodide (PI) Assay
  • Annexin V and 7-AAD Assay
  • Lactate Dehydrogenase (LDH) Release Assay

Apoptosis Assays

Early Stage Apoptosis Detection Assays

  • Annexin V assay and 7-AAD Assay
  • Mitochondrial Membrane Potential Assay
  • Cytochrome C Release Assay

Mid-Stage Apoptosis Assays

  • Caspase Activity Assays

Late-Stage Apoptosis Assays

  • DNA Fragmentation Assay

Details: cell-toxicity-apoptosis-inhibition-of-proliferation

Need Help or Have Questions on Cell-Based Assays?

Contact us to discuss the specifics of your project. Our team of experienced scientists is ready to assist you with tailored solutions to meet your unique needs. Whether you need help with assay development, FDA IND, stability study,  lot release approval, or other scientific endeavors, we are here to support you.
Contact us to learn more about our cell based assay services

We will initiate your project as soon as the proposal is approved and signed by you. Our streamlined process ensures a quick start, minimizing delays and maximizing efficiency. Fill out the form below to email us or click our live chat option to speak with a MarinBio Scientist and get your project underway.

Yes, we have over 30 years of expertise in developing and validating cell based assays for FDA IND, lot release or stability study approval. Our team can also liaise directly with the FDA on your behalf, ensuring a smooth and compliant process. Please contact us to learn more about how we can assist you with your assay development and FDA approval needs.

MarinBio scientists are experienced and creative in designing, developing, validating assays. Some of the assays we perform are listed below, but there are many more that we created, developed and validated. Give us call so that we may help you.

Need help or have questions on cell based assays?

Give us a call at 415-883-8000

Contact Us about Our Cell Based Assays Services

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