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Large Study Finds Gene Therapy Using AAV Has a Very Low Risk of Causing Liver Cancer

    Introduction Recombinant adeno-associated virus (rAAV) vectors have become the leading platform for in vivo gene therapy, transforming the treatment of numerous inherited diseases,

Editing the Powerhouse: Mitochondrial Genome Editing for Human Gene Therapy

    Why Mitochondrial DNA Matters Mitochondria are the energy-producing organelles of human cells. Unlike most cellular structures, mitochondria possess their own small genome known

A New Biological Gene Clock Predicts Ageing, Disease, and How Long We Will Live

  The Problem of Measuring Age Chronological age does not accurately reflect biological ageing. Two individuals of the same age can differ greatly in disease

Robin: The AI Scientist That Performs Scientific Discovery – And Discovered a New Drug Candidate for Blindness

    Researchers from FutureHouse have developed Robin, a groundbreaking multi-agent artificial intelligence system capable of autonomously generating scientific hypotheses, proposing experiments, analyzing biological data,

Can Supplements Slow Aging? Large Epigenetic Study Reveals Surprising Clues

    Can a supplement make the body biologically younger? That is one of the most exciting — and controversial — questions in aging research.

A New Drug Combines Five Targets in One Molecule to Combat Obesity and Diabetes- and It Outperforms Ozempic in Mice

    A new study published in the journal Nature describes a highly engineered metabolic drug that combines five distinct therapeutic activities into a single

RNA-Triggered Programmable Cell Elimination with CRISPR–Cas12a2 Technology

      The selective elimination of cells based on their genetic or transcriptional identity is a longstanding challenge in biology and medicine. Whether the

Why Ageing Makes Cancer More Dangerous-And How Tumors Hijack Cellular Stress Pathways to Spread

A growing body of evidence suggests that ageing does far more than increase the risk of developing cancer. It fundamentally changes the biology of the

Eating Well May Slow Your Biological Clock – And Save Your Life

New research links diet quality to epigenetic aging and mortality risk in tens of thousands of Americans A growing body of research suggests that aging

Human-Centric Drug Development: The New Approach Methodologies (NAMs) Revolution

Introduction: A Field at an Inflection Point Drug development today sits at a paradox that has become increasingly difficult to ignore. Scientific capability has advanced

Losartan and Longevity: Can a Common Blood Pressure Drug Turn Back the Aging Clock?

  A 2026 study published in Aging Cell by researchers from Johns Hopkins University and the National Institute on Aging provides compelling support for this

PROTAC for COPD: Precision Senolytic Targeting of Senescent Cells

  Researchers at Imperial College London, in collaboration with AstraZeneca, have demonstrated that a next-generation proteolysis-targeting chimera can hunt down and eliminate the zombie-like senescent

DNA Without a Template? Scientists Just Rewrote a Rule of Life

Stanford researchers have discovered a bacterial immune enzyme that writes genetic code without using any DNA or RNA as a guide, upending a fundamental assumption

From Sequence to Cure: The Cell-Free Protein Synthesis (CFPS) in AI-Generated Antibody Revolution

  The Antibody Renaissance: Why AI Arrived at Precisely the Right Moment Monoclonal antibodies (mAbs) represent the most productive drug class of the modern biopharmaceutical

The Rising Tide: Why Cancer Is Striking Younger, and What Science Is Doing About It

  A New and Troubling Pattern Cancer has long been understood as a disease of aging, arising from the gradual accumulation of somatic mutations, cellular

mRNA Lipid Nanoparticle-Mediated Delivery of Monoclonal Antibodies: A Platform Technology for Immunotherapy

  Monoclonal antibodies (mAbs) have become one of the most powerful therapeutic tools in modern medicine, particularly in the fight against viral pathogens. Highly potent

SPYTACs: A Novel Platform for Targeted Amyloid-β Degradation in Alzheimer’s Disease

    Alzheimer’s disease (AD) remains one of the most devastating neurodegenerative disorders worldwide, affecting an estimated 57 million individuals. Despite recent clinical advances in

Could Artificial Intelligence (AI) Catch Your Next Heart Attack Before You Do?

  Artificial intelligence (AI) has been steadily moving into medical imaging, but until now most systems have functioned like narrow specialists, trained to answer one

mRNA Lipid Nanoparticle Delivery of Monoclonal Antibodies: A Platform Technology for Immunotherapy

mRNA lipid nanoparticle (LNP) technology has significantly changed the field of immunotherapy. It first became widely known for helping develop COVID-19 vaccines بسرعة and effectively.

Can Lifestyle Rewire Biological Aging? Insights From Epigenetic Clocks and New Evidence From Frailty Research

  Lifestyle Intervention Slows Biological Aging in Frail Older Adults Aging has traditionally been regarded as a unidirectional biological process driven by time and genetics.