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Introduction Recombinant adeno-associated virus (rAAV) vectors have become the leading platform for in vivo gene therapy, transforming the treatment of numerous inherited diseases,
Why Mitochondrial DNA Matters Mitochondria are the energy-producing organelles of human cells. Unlike most cellular structures, mitochondria possess their own small genome known
The Problem of Measuring Age Chronological age does not accurately reflect biological ageing. Two individuals of the same age can differ greatly in disease
Researchers from FutureHouse have developed Robin, a groundbreaking multi-agent artificial intelligence system capable of autonomously generating scientific hypotheses, proposing experiments, analyzing biological data,
Can a supplement make the body biologically younger? That is one of the most exciting — and controversial — questions in aging research.
A new study published in the journal Nature describes a highly engineered metabolic drug that combines five distinct therapeutic activities into a single
The selective elimination of cells based on their genetic or transcriptional identity is a longstanding challenge in biology and medicine. Whether the
A growing body of evidence suggests that ageing does far more than increase the risk of developing cancer. It fundamentally changes the biology of the
New research links diet quality to epigenetic aging and mortality risk in tens of thousands of Americans A growing body of research suggests that aging
Introduction: A Field at an Inflection Point Drug development today sits at a paradox that has become increasingly difficult to ignore. Scientific capability has advanced
A 2026 study published in Aging Cell by researchers from Johns Hopkins University and the National Institute on Aging provides compelling support for this
Researchers at Imperial College London, in collaboration with AstraZeneca, have demonstrated that a next-generation proteolysis-targeting chimera can hunt down and eliminate the zombie-like senescent
Stanford researchers have discovered a bacterial immune enzyme that writes genetic code without using any DNA or RNA as a guide, upending a fundamental assumption
The Antibody Renaissance: Why AI Arrived at Precisely the Right Moment Monoclonal antibodies (mAbs) represent the most productive drug class of the modern biopharmaceutical
A New and Troubling Pattern Cancer has long been understood as a disease of aging, arising from the gradual accumulation of somatic mutations, cellular
Monoclonal antibodies (mAbs) have become one of the most powerful therapeutic tools in modern medicine, particularly in the fight against viral pathogens. Highly potent
Alzheimer’s disease (AD) remains one of the most devastating neurodegenerative disorders worldwide, affecting an estimated 57 million individuals. Despite recent clinical advances in
Artificial intelligence (AI) has been steadily moving into medical imaging, but until now most systems have functioned like narrow specialists, trained to answer one
mRNA lipid nanoparticle (LNP) technology has significantly changed the field of immunotherapy. It first became widely known for helping develop COVID-19 vaccines بسرعة and effectively.
Lifestyle Intervention Slows Biological Aging in Frail Older Adults Aging has traditionally been regarded as a unidirectional biological process driven by time and genetics.