Download the full article (PDF) Introduction The emergence of chimeric antigen receptor (CAR)-based immunotherapies has revolutionized the treatment of hematologic malignancies. While CAR-T cell therapies dominate the clinical landscape, enthusiasm is growing for CAR-engineered natural killer (CAR-NK) cells, which leverage the cytotoxic capacity of NK cells with the specificity of CAR constructs. Natural killer (NK) […]
Download the full article (PDF) Introduction The emergence of chimeric antigen receptor (CAR)-based immunotherapies has revolutionized the treatment of hematologic malignancies. While CAR-T cell therapies dominate the clinical landscape, enthusiasm
Introduction Cell-based high throughput screening (HTS) platforms have significantly accelerated drug discovery by providing high-content, scalable, and clinically relevant data early in the screening pipeline. Cell-based assays have become indispensable
The landscape of cancer immunotherapy is rapidly evolving with the emergence of several cutting-edge modalities. Some examples include genetically engineered chimeric antigen receptor (CAR) immune cell subsets, neoantigen vaccines
In a recent article published in Molecular Therapy, researchers from Voyage Therapeutics reported the development of a novel adeno-associated virus (AAV) capsid capable of crossing the blood-brain barrier (BBB)
The U.S. Food and Drug Administration (FDA) is spearheading a transformative shift in preclinical drug safety testing through a comprehensive roadmap aimed at reducing and ultimately replacing animal studies with
Introduction Two unsung hero hormones—Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) have emerged as targets for groundbreaking therapies that reshape the way we approach diabetes treatment and weight loss
Press Release | Marin Biologic Labs Achieves Flawless FDA Inspection for Second Consecutive Year, Expands Biopharmaceutical Services What are PROTACs? Proteolysis Targeting Chimeric (PROTAC) drugs are innovative molecules that utilize
What is a Cell Based Assay? A cell based assay uses live cells to quantify biological processes and evaluate cellular responses to various stimuli. These assays provide a more physiologically
Lung cancer is among the most lethal malignancies worldwide, with limited therapeutic success despite advancements in immunotherapy. Immune checkpoint inhibitors (ICIs), particularly those targeting PD-1/PD-L1 pathways, have marked a paradigm
A groundbreaking study published in the journal Cell has unveiled a pivotal role for the immune system in suppressing the spread of breast cancer (1). The research highlights how
