November 6, 2025
In developing optimal cell based assays experience is key. A number of parameters are taken into account for each experiment.
Knowing your cells, following their appearance during culture is essential for the best assay results. Appropriate media, supplements and serum selection for each cell line / primary cell type must be taken into account. Growth rate, passage number and conditions are key considerations, as each cell line and cell type is unique. At MarinBio, each cell line is carefully documented regarding source, purity, cell banking, passage number and culture conditions to ensure all details are recorded. All of these details plus many more are taken into consideration to ensure excellent data quality and reproducibility.
Because of our extensive experience in The Art of Cell Culture we take into consideration multiple factors for optimal assay development.
Cell line Selection for Assay Development
Some factors we take into consideration include the following
Tissue Derived Primary Cells and Assays
Depending on the therapeutic modality, indication and target, assays with primary human cells may be important for translational research.
Assay conditions will vary, depending on the stimulation and mechanistic response of each cell type.
Multiple primary cell types are available to test your drug of interest.
Media, Serum and Supplements
Whether the assay uses cell lines or primary tissue cells, optimal culture conditions are required.
Media
Serum conditions
Supplements
Quality Control
Documentation and record keeping of cell line history and culture conditions.
We will initiate your project as soon as the proposal is approved and signed by you. Our streamlined process ensures a quick start, minimizing delays and maximizing efficiency. Fill out the form below to email us or click our live chat option to speak with a MarinBio Scientist and get your project underway.
Yes, we have over 30 years of expertise in developing and validating cell based assays for FDA IND, lot release or stability study approval. Our team can also liaise directly with the FDA on your behalf, ensuring a smooth and compliant process. Please contact us to learn more about how we can assist you with your assay development and FDA approval needs.
MarinBio scientists are experienced and creative in designing, developing, validating assays. Some of the assays we perform are listed below, but there are many more that we created, developed and validated. Give us call so that we may help you.
Give us a call at 415-883-8000
For More Information about our cell based assay services, please use the following informational form