Flow Cytometry

• Cell phenotyping, cell differentiation, T-lymphocyte subset analyses
• Ligand-binding, -inhibition and -specificity of binding
• Cell-activation, -growth inhibition, -proliferation,
• MLR (Mixed Lymphocyte Reaction)
• Apoptosis
• Gene expression
• Protein expression
• Drug-induced-signaling pathways, cytokine production
• Multiplex quantitation of different analytes in a single sample
• Protein post-translational modifications, including cleaved and phosphorylated proteins to study intracellular signaling pathways
• Cell cycle analyses, providing a powerful tool to assess cells in G0/G1 phase versus S phase, G2 phase or polyploidy and including analyses of cell proliferation and cell activation
• Cell health and metabolic status, ranging from cell viability to late stage programmed cell death

Other Capabilities:

• Isolation of single cells with desired phenotypic characteristics by a process called cell sorting.
• Cell-based applications include analyzing cell metabolism, cell-health, cell viability, small molecules, nucleic acids (DNA and RNA), proteins, or chromosomes