Covid-19

Covid-19

Implications of Omicron BA.5 for Future Vaccine Development

As new cases of COVID-19 soar, experts warn about the newly emerged COVID subvariant BA.5, a sub-lineage of BA.2. Subvariants of Omicron BA.1 emerged in 2021, BA.2 in early 2022 and BA.5 came in April 2022. BA.5 dominates globally, replacing BA.2. The BA.1 and BA.2 attach the upper respiratory tract, whereas, the BA.5 damages the […]

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Covid-19

Implications of Omicron BA.5 for Future Vaccine Development

As new cases of COVID-19 soar, experts warn about the newly emerged COVID subvariant BA.5, a sub-lineage of BA.2. Subvariants of Omicron BA.1 emerged in 2021, BA.2 in early 2022

Assay Development

Astrocyte Infections and Long-COVID Symptoms

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected hundreds of millions of individuals worldwide, disrupting public health and the economy. Post-COVID (or Long-COVID), the collection of symptoms and pathophysiologies

Covid-19

New Insights into Omicron BA.5 Subvariant

As new cases of COVID-19 soar, experts warn about the newly emerged COVID subvariant BA.5, a sub-lineage of BA.2. Subvariants of Omicron BA.1 emerged in 2021, BA.2 in early 2022

Assay Development

Insights into COVID-19 Vaccine Antibody Production

Now that Christmas and many other celebrations gather people around a table, it is important to know about the risks we take and the science behind them. Vaccines are the

Assay Development

Protection Offered by COVID-19 Vaccines Against Variants

Efficacy of mRNA vaccines on SARS-CoV-2 variants (UK and South Africa) Detection of mutations arising in the genome of the SARS-CoV-2 virus responsible for COVID-19 have led to concerns that

Assay Development

Factors Contributing to SARS-CoV-2 Virulence

SARS-CoV-2 is more virulent than SARS-CoV (identified in 2003), because it binds to host cells with greater affinity, and more recently (see below) uses another receptor to increase virus uptake

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Adaptive Immunity Against Viral Threats

Innate Immunity and Adaptive Immunity Innate immunity is the initial immune response to infectious agents, carried out mainly by granulocytes and macrophages. These include a variety of responses that are genetically

Mechanisms of Immune Response to Viral Infection

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Decoding Immune Mechanisms to Viral Infections

T Cell and Innate Immune Responses to Viral Infection – Implications for the Pandemic While much of the focus on treating COVID-19 and preventing its spread has been on antibodies,

Vaccine Development Strategies to SARS-CoV-2

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Strategies for SARS-CoV-2 Vaccines

Vaccine development is protracted and risky. On average, vaccines take more than 10 years to move from the preclinical phase to approval, and the probability of market entry for any

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Current Progress of COVID-19 Vaccines in Trials

The unprecedented scale of scientific effort being applied to countering the pandemic is already beginning to bear fruit. Current estimates of the infection fatality rate (IFR) have been lowered to